Fig. 8

Reclustering analysis of tumor-infiltrating cDCs and macrophages. a T-distributed stochastic neighbor embedding (t-SNE) plot for cDCs. b t-SNE plot for the treatment group-specific distribution of cDC subclusters. c Violin plots showing cDC subcluster-specific gene profiles. d Heatmap depicting the results of GSEA using KEGG gene sets for cDC subclusters. e Histogram representing the proportion of cDC subcluster in each group. f Heatmap depicting the results of GSEA using KEGG gene sets for Fcscn1⁺ cDC1 subclusters. g t-SNE plot for macrophages. h t-SNE plot for the treatment group-specific distribution of macrophage subclusters. i Violin plots showing macrophage subcluster-specific gene profiles. j Heatmap showing the results of GSEA using KEGG gene sets for macrophage subclusters. k Histogram representing the proportion of macrophage subcluster in each group. l Violin plots showing macrophage classical activation-associated gene levels in different treatment groups. m Heatmap depicting the results of GSEA using KEGG gene sets for Ly6c2⁺ M1-like subclusters. *p < 0.05 means the significant difference compared to MSA-2 combined with YM101