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Table 3 Recommendations of neurocognitive assessment for PCNSL patients at baseline and follow-up

From: Evidence-based expert consensus on the management of primary central nervous system lymphoma in China

Cognitive area

Recommended tests [37, 38]

Tests suitable for patients in China

Time (min)

General

MMSE

MMSE

5–10

MoCA

5–10

Premorbid IQ estimation

Barona index

Wechsler Adult Intelligence Scale

5

Attention/executive

Digits forward and backward span; trail making test (Parts A and B)

Digit span

5

Trail making test (A, B)

5–10

Stroop test

5–10

Verbal memory

Hopkins verbal learning test-revised

AVLT-Huashan

10

Word fluency

Not mentioned

BNT

5

Animal verbal fluency test

1

Motor

Grooved pegboard test

Grooved Pegboard test

15–20

Visuospatial ability

Not mentioned

Clock-drawing test

5

Rey–Osterrieth complex figure test

15–40

QoL

EORTC-QLQ-C30

EORTC QoL questionnaire

10

BCM 20

Evaluation of brain function in cancer treatment

10–15

  1. There were two systematic reviews identifying cognitive domains and tests to be assessed for PCNSL. One was conducted by Correa et al. [38], and the other was by van der Meulen et al. [37]. The evidence evaluation group adopted and combined their results as “Recommended tests.” Time: duration needs to be taken for each test. MMSE: mini-mental state examination. MoCA: Montreal Cognitive Assessment
  2. IQ Intelligence Quotient, AVLT Huashan: Auditory Verbal Learning Tests—Huashan version, BNT Boston naming test, QoL quality of life