Myelofibrosis (n = 10) | ET and PV (n = 32) | p | |
---|---|---|---|
Day 0 (first dose) | |||
Geometric mean concentration (95% CI), AU/mL | 4.20 (3.8–4.93) | 4.18 (3.87–4.65) | 0.716** |
Day 21 (second dose) | |||
Geometric mean concentration (95% CI), AU/mL | 5.76 (4.22–8.78) | 21.83 (16.22–29.72) | 0.001** |
Seroconversion rate (i.e., Responders), n (%) | 1 (10) | 22 (68.8) | 0.002*** |
Day 35 (two weeks after second dose) | |||
Geometric mean concentration (95% CI), AU/mL | 32.47 (12.09–84.58) | 217.97 (135.07–324.35) | 0.003** |
Seroconversion rate (i.e., Responders), n (%) | 6 (60%) | 30 (93.8%) | 0.021*** |