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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: N6-methyladenosine methyltransferases: functions, regulation, and clinical potential

Fig. 2

m6A methyltransferase regulation of the core pathways in cancer. The key cancer pathways, including the MYC pathway (a), Wnt/β-Catenin pathway (b), PI3K/AKT/mTOR pathway (c), p53 (d), BCL-2 (e), and other key genes (f), are regulated by the m6A methyltransferases METTL3/METTL14/WTAP. The schematic illustration shows the core genes in the related pathway that target different m6A methyltransferases, as well as the modulated upstream and downstream genes in these pathways

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