Fig. 2From: N6-methyladenosine methyltransferases: functions, regulation, and clinical potentialm6A methyltransferase regulation of the core pathways in cancer. The key cancer pathways, including the MYC pathway (a), Wnt/β-Catenin pathway (b), PI3K/AKT/mTOR pathway (c), p53 (d), BCL-2 (e), and other key genes (f), are regulated by the m6A methyltransferases METTL3/METTL14/WTAP. The schematic illustration shows the core genes in the related pathway that target different m6A methyltransferases, as well as the modulated upstream and downstream genes in these pathwaysBack to article page