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Table 3 The PK profiles of BMS-986205

From: Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors in clinical trials for cancer immunotherapy

Species

CL (mL/min/kg)

Vss (L/kg)

t1/2 (h)

F (%)

Rat

27

3.8

3.9

4

Dog

25

5.7

4.7

39

Cyno

19

4.1

6.6

10

  1. CL, plasma clearance; Vss, volume distribution stead state; t1/2, half-life; F, oral bioavailability; Cyno, cynomologous monkeys
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Journal of Hematology & Oncology

ISSN: 1756-8722

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