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Table 3 Multivariate analysis results

From: Allogeneic hematopoietic cell transplantation provides effective salvage despite refractory disease or failed prior autologous transplant in angioimmunoblastic T-cell lymphoma: a CIBMTR analysis

 

Number

RR

95% CI lower limit

95% CI upper limit

P-value

Overall p value

Chronic GVHD

 ATG/alemtuzumab

  No

174

1

   

0.02

  Yes

55

0.58

0.36

0.93

0.02

 

Progression/Relapse

 No significant covariates

Non-relapse mortality

 No significant covariates

Progression-free survival

 Disease status

  CR

108

1

   

0.03

  PR

90

1.13

0.76

1.66

0.54

 

  Chemoresistant

38

1.73

1.08

2.77

0.02

 

  Missing/Untreated

13

0.43

0.15

1.20

0.11

 

Overall survival

 Karnofsky performance score (≤ 6 months)a

  ≥ 90%

119

1

   

0.002

  < 90%

113

3.46

1.74

6.87

0.0004

 

  Missing

17

1.95

0.54

6.98

0.31

 

 Karnofsky performance score (> 6 months)a

  ≥ 90%

106

1

   

0.28

  < 90%

80

0.66

0.39

1.12

0.12

 

  Missing

14

0.73

0.29

1.86

0.51

 
  1. GVHD graft-versus-host disease, CI confidence interval, ATG anti-thymocyte globulin, CR complete remission, PR partial remission, RR relative risk
  2. Variables tested in the Multivariate analysis are listed in Additional file 1 Table S2
  3. a6-months was chosen as cut-off based on the maximum likelihood value in the Cox model
  4. p-value <0.05 is considered significant