Fig. 1

Pharmacokinetic analyses of chiauranib. a The mean plasma concentration-time curves of chiauranib in patients at a single-oral dose of 10, 20, 35, 50, and 65 mg chiauranib. The mean plasma concentration-time curves (b) and AUC-dose linear regression (c) of chiauranib on day 28 in the first treatment cycle at a multiple oral dose of 10, 20, 35, 50, and 65 mg chiauranib