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Table 6 The list of significantly correlated DNA methylation and the expression of the intronic and intergenic methylated lncRNAs (n = 5) from DUX4 BCP-ALL subtypes

From: Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia

DM lncRNAs

Absolute fold change

Methylation value

Pearson correlation rate

P value

Epi-markers

Biotype

RP11-134O21.1

2.54

− 1.56

− 0.63

1.9E−010

Enhancer

Intron

RP11-398B16.2

2.08

− 1.85

− 0.47

0.0007

Insulator

RP11-689B22.2

1.52

− 3.37

− 0.47

0.008

Enhancer

CTC-458I2.2

− 1.16

3.38

− 0.42

0.0001

Enhancer

LINC00880

− 1.45

2.23

− 0.25

0.02

Enhancer

Intergenic

  1. The significance is calculated based on Pearson correlation rate and two-tailed P value ≤ 0.05. The lncRNAs are promoter differentially methylated and differentially expressed in their corresponding subtypes. These lncRNAs are with enhancer and insulator epigenetic markers. DM, differentially methylated