Fig. 2
From: Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia
The molecular pathways of lncRNAs involved in the DUX4 and Ph-like BCP-ALL subgroups. a The barplot plot depicts the molecular pathway analysis from the functional enrichment analysis for nearby (≤ 100 kb proximity) cis protein-coding genes correlated (Pearson correlation coefficient ≥ 0.55 and two-tailed P value ≤ 0.05) with DE lncRNAs in the DUX4 subtype. b The heatmap depicts the concordance between the protein-coding and lncRNA-based predictions for DUX4 subtypes. c The barplot depicts the molecular pathway analysis from the functional enrichment analysis for nearby (≤ 100 kb proximity) cis protein-coding genes correlated (Pearson correlation coefficient ≥ 0.55 and two-tailed P value ≤ 0.05) with DE lncRNAs in the Ph-like subtype. d The heatmap depicts the overlapping pathways from both lncRNAs and protein-coding in the Ph-like subtype. The KEGG pathways or biological functions presented in the heatmaps and barplots show with P value ≤ 0.05 and > 2 genes involved in each pathways. The hypergeometric P values are obtained from GeneSCF for the pathways. CAMs cell adhesion molecules, CML chronic myeloid leukemia, AML acute myeloid leukemia