Table 2 Univariate and multivariate analysis of clinic pathologic factors for overall survival in 120 patients with CRC
From: lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer
Risk factors | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P valuea | HR (95% CI) | P valuea | |
SNHG6 expression (low vs. high expression) | 3.24 (1.84–5.86) | < 0.001 | 2.48 (1.60–5.86) | 0.002 |
TNM stage (I/II vs. III/IV) | 2.72 (1.48–4.88) | < 0.001 | 1.24 (0.48–2.74) | 0.658 |
Tumor invasion depth (T1/T2 vs. T3/T4) | 1.62 (0.82–2.84) | 0.184 |  |  |
Lymph node metastasis (N0 vs. N1 or above) | 1.62 (0.77–2.81) | 0.622 |  |  |
Distant metastasis (M0 vs. M1) | 4.82 (2.52–8.96) | < 0.001 | 4.06 (1.83–8.87) | 0.001 |
Age (≤ 60 vs. > 60) | 0.97 (0.58–1.66) | 0.892 |  |  |
Gender (male vs. female) | 0.92 (0.52–1.60) | 0.584 |  |  |