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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer

Fig. 5

SNHG6 promotes CRC growth and metastasis in vivo. a Representative image of tumors formed in nude mice from empty vector, sh-SNHG6#1 vector and SNHG6 overexpression vector groups, and the tumor volume growth curves of different groups. b SNHG6 expression was detected in tumors from the different groups of mice by qRT-PCR. c Left panel, representative images of the gross lesion in lung tissues and hematoxylin and eosin (HE) staining of metastatic nodules in the lungs from the different groups. Right panel, the statistical result of metastatic nodule numbers in the lungs from the different groups. d Left panel, representative images for HE-staining, Ki67, E-cadherin, and vimentin immunostaining of tumor samples from the different groups. Right panel, the statistical results of these immunochemistry assays. Scale bar = 50 μm. *P < 0.05, **P < 0.01, and ***P < 0.001

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