Fig. 2
Memory T cell subset distribution in CD4+ and CD8+ T cells in patients younger or older than 60 years with AML and AML-CR. a, b TSCM, TCM, TEM, and TEF subsets within the CD4+ (a) and CD8+ (b) populations in the HIy, AMLy, HIo, and AMLo groups. HIy (n = 13), AMLy (n = 10), HIo (n = 14), and AMLo (n = 10). c, d: Frequency of TSCM, TCM, TEM, and TEF cells within the CD4+ (c) and CD8+ (d) T cell populations in age matched HI, AML and AML-CR cohorts. HIs (n = 13), AML (n = 10), and AML-CR (n = 10). e, f Five AML patients were dynamically assayed for the TSCM, TCM, TEM, and TEF subsets in the CD4+ (e) and CD8+ (f) T cell populations at different time points. AML-CR, AML patients who achieved complete remission; P, patient; CR1, 2, 3, indicate different time points at which the patient achieved CR