Skip to main content
Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells

Fig. 2

Mitochondria transfer from Jurkat cells to MSCs can be blocked by cytochalasin D. a Representative confocal microscopy images show the presence of TNTs containing mitochondria (arrow). Scale bar, 5 μm. b 18-α-GA (50 μM), dynasore (50 μM), or cytochalasin D (1 μM) was added to the coculture system with ara-C or MTX for 48 h. Flow cytometry analysis of Jurkat cell-derived mitochondria uptake by MSCs (GFP+ gated). c The percentage of Red+ MSCs in each group was analyzed and graphed. The results are expressed as the mean ± S.E.M. of three independent experiments (*P < 0.05; **P < 0.01; t test)

Back to article page