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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: CAR-T cells targeting CLL-1 as an approach to treat acute myeloid leukemia

Fig. 1

Expression of CLL-1 in AML and normal cells. a CLL-1 expression on AML cell lines U937, HL60, NB4, THP-1, and Molm13. The percentages of CLL-1+ cells of each sample are indicated. b Variant CLL-1 expression levels among primary AML samples. CLL-1 staining from eight representative samples is shown. c Distribution of CLL-1+, CD33+, and CD34+ cells in primary AML samples (n = 37–40, from a diverse range of AML subtypes; see Additional file 1: Table S1); NS not significant. d CLL-1 expression on CD34+CD38− LSCs within AML bone marrow. e CLL-1 expression on CD34+ cells within normal bone marrow. f CLL-1 expression on normal peripheral blood cells. One representative experiment of three is shown. HSC hematopoietic stem cell, NK natural killer

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