Fig. 2From: Novel agents for pancreatic ductal adenocarcinoma: emerging therapeutics and future directionsMechanism of action of different therapeutic strategies for PDAC. They include cytotoxic agents, PARP inhibitors, CDK inhibitors, MEK/ERK inhibitors, PI3K/AKT/mTOR inhibitors, Hedgehog inhibitors, Notch inhibitors, STAT 3 inhibitors, VEGFR inhibitors, monoclonal antibodies, GVAX/CRS-207, anti-PD-1/PD-L1 antibodies, and CAR-T cell therapyBack to article page