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Table 1 Exosomal proteins as potential diagnostic markers in various tumors

From: Exosomal proteins as potential markers of tumor diagnosis

Exosomal proteins

Tumor

Body fluid

Isolation method

Detection method

Year

Ref

NY-ESO-1

Lung

Plasma

Extracellular Vesicle Array

Extracellular Vesicle Array

2016

[66]

PKG1, RALGAPA2, NFX1, TJP2

Breast

Plasma

Ultracentrifugation

Parallel reaction monitoring (PRM)

2017

[2]

Her2

Breast

Plasma

Microfluidic chip

Microfluidic chip

2017

[70]

Glypican-1

Breast

Serum

Ultracentrifugation and FACS

FACS

2016

[5]

Glypican-1

Pancreatic

Serum

Ultracentrifugation and FACS

Flow-cytometry and ELISA

2016

[5]

Glypican-1

Colorectal

Plasma

Immunocapture assays

Flow-cytometry

2017

[76]

CEA

Colorectal

Serum

Polymer precipitation

ELISA

2017

[46]

AMPN

VNN1, PIGR

Cholangiocarcinoma

Serum

Ultracentrifugation

Western blot

2016

[77]

PSA

Prostate

Plasma

Filtration and ultracentrifugation

ELISA and nanoscale flow-cytometry

2017

[41]

GGT1

Prostate

Serum

Ultracentrifugation/DGC/SEC

Western blot and fluorescent probe

2017

[80]

CD24, EpCAM,

CA-125

Ovarian

Plasma

Microfluidic ExoSearch Chip

Microfluidic ExoSearch Chip

2016

[86]