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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Superior GVHD-free, relapse-free survival for G-BM to G-PBSC grafts is associated with higher MDSCs content in allografting for patients with acute leukemia

Fig. 2

Suppressive activity of MDSCs isolated from G-BM and G-PBSC grafts. a The proliferation of purified and CFSE-labled CD3+ T cells in the coculture with isolated MDSCs or not. b The inhibition rate of the proliferation of CD3+ T cells by MDSCs. Isolated MDSCs were added at a 1:1 and 1:5 ratio to purified CD3+ T cells in the presence of anti-CD2/CD3/CD28 biotin beads according to manufacturer instructions (Miltenyi Biotec). Data are representative of three independent experiments (NS P > 0.05, **P < 0.01)

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