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Table 2 Transplantation outcomes

From: Comparison of matched sibling donors versus unrelated donors in allogeneic stem cell transplantation for primary refractory acute myeloid leukemia: a study on behalf of the Acute Leukemia Working Party of the EBMT

 

MSD (n = 660)

UD (n = 381)

p value

Engraftment

606 (94.2%)

359 (95.2%)

0.5

Acute GVHD

  

0.012

 Grade 0–I

447 (72.1%)

236 (64.5%)

 

 Grade II–IV

173 (27.9%)

130 (35.5%)

 

Outcome at 2 years

 Leukemia-free survival

25.3% (21.6–28.9)

28.3% (23.3–33.3)

0.56

 Overall survival

30.9% (27–34.9)

34.3% (29–39.7)

0.57

 Relapse

53.7% (49.6–57.7)

46.4% (40.9–51.7)

0.04

 Non-relapse mortality

21% (17.9–24.4)

25.1% (21.7–28.6)

0.11

Chronic GVHD

28.9% (24.9–33)

25.8% (20.8–31)

0.77

  1. Data are n (%) or n (%; 95% CI)
  2. MSD matched sibling donors, UD unrelated donors, GVHD graft-versus-host disease