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Fig. 8 | Journal of Hematology & Oncology

Fig. 8

From: A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type γ in chronic myeloid leukemia patients

Fig. 8

PTPRG expression in various leukocyte populations of CML patients at diagnosis and after treatment. a Representative flow cytometric analysis of PTPRG protein at diagnosis and at follow-up following successful TKI-based treatment. At diagnosis, monocytes and PMN downregulate PTPRG expression. After an average of 6 months of treatment, the levels of phosphatase expression recover and become similar to healthy donors. b Box-Whisker diagram displays significant differences between PTPRG expression in monocytes and PMN populations in three different CML patients at diagnosis and after treatment (statistical analyses are indicated on graphs). c The table summarizes the mean fluorescence intensity (MFI) values related to PTPRG expression shown in panel b

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