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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

Fig. 2

Expression of Blimp-1 correlates with the upregulation of inhibitory receptors on T cells from AML patients. Flow cytometry analysis of expression of PD-1, TIGIT, 2B4, CD160, and TIM-3 on Blimp-1− vs. Blimp-1+ T cells from AML patients (n = 24). Blimp-1 mRNA expression are detected by SmartFlare. Data of CD4+ (a) and CD8+ (b) T cells are shown. Panels on the right of each set of representative histograms are plots of expression of each receptor on Blimp-1− vs. Blimp-1+ T cells. P values were obtained by paired t test and Wilcoxon signed-rank test.

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