Fig. 8From: Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomasIn vivo evaluation of the effect of combining nutlin and PD0332991. a Tumour growth in mice injected with IB115 cells and treated with either vehicle, nutlin, PD0332991 or a combination of the two drugs. There were eight mice in each group. b Event-free analysis: for each mouse, the tumour volume was monitored, and a twofold increase in tumour volume was considered to be an eventBack to article page