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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Combined targeting of MDM2 and CDK4 is synergistic in dedifferentiated liposarcomas

Fig. 2

a Effect of PD0332991 on dedifferentiated liposarcoma (IB115 and IB111), myxofibrosarcoma (IB114), leiomyosarcoma (IB136) and osteosarcomas (IB128) cell lines. The IC50 values are 1.3, 4, 1.2,1.3 and 1 μM, respectively. b Western blot analysis of p-Rb, Rb total and GAPDH in the 5 cell lines, which were either untreated or exposed to PD0332991. c Quantification of Western blot analyses for IB111, IB114, IB115, IB128 and IB136 cells treated or not at the IC50 of PD0332991

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