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Fig. 7 | Journal of Hematology & Oncology

Fig. 7

From: The chimeric monoclonal antibody MHCSZ-123 against human von Willebrand factor A3 domain inhibits high-shear arterial thrombosis in a Rhesus monkey model

Fig. 7

VWF occupancy after administration of MHCSZ-123. At 15 min after injection, the mean VWF occupancy was 33% at 0.1 mg/kg, 51% at 0.3 mg/kg, and 94% at 0.6 mg/kg, respectively. The binding was stable by 1 h after injection. At 2 h after administration, occupancy was still observed. Data represent mean ± SD (n = 6 animals per group)

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