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Fig. 6 | Journal of Hematology & Oncology

Fig. 6

From: An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets

Fig. 6

Global miRNA differential expression and overlap in the Boston and Utah datasets. a Global miRNA differential expression between high- and low-risk subtypes in the Boston dataset (left panel) and the Utah dataset (right panel). Blue dots represent probes with statistically significant differential expression. b Overlap between the Boston and Utah datasets in terms of miRNAs shown in a. Left panel shows the total overlap of all differentially expressed miRNAs. Right panel shows the overlap in miRNAs upregulated in high-risk subtypes (hypergeometric test p < 0.0001 for the overlap in both comparisons). Overlap in miRNAs downregulated in high-risk subtypes was smaller but still statistically significant (p < 0.01)

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Journal of Hematology & Oncology

ISSN: 1756-8722

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