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Table 3 Stepwise Cox regression analysis of survival

From: Mutations of CREBBP and SOCS1 are independent prognostic factors in diffuse large B cell lymphoma: mutational analysis of the SAKK 38/07 prospective clinical trial cohort

  OS EFS PFS
Variable p value HR (95% CI) p value HR (95% CI) p value HR (95% CI)
CREBBP mut or EP300 mut 0.013 4.41 (1.38–14.16) 0.021 2.53 (1.15–5.54) 0.041 2.94 (1.05–8.27)
Failure to achieve complete remission 0.032 0.27 (0.08–0.89) 0.0006 0.22 (0.097–0.53) 0.001 0.17 (0.056–0.49)
International Prognostic Index (IPI) 0.86 0.96 (0.61–1.51) 0.38 0.88 (0.66–1.17) 0.646 1.09 (0.75–1.60)