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Table 3 Multivariate analysis using a Cox proportional hazards model, N = 90. Only variables with p < 0.05 in univariate analysis. LFS, OS and RI

From: Allogeneic stem cell transplantation in adult patients with acute myeloid leukaemia and 17p abnormalities in first complete remission: a study from the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT)

 

p

HR

95% CI

LFS

Age ≥50 years old

0.48

1.23

0.69

2.20

RIC vs MAC

0.13

1.54

0.89

2.68

MK

0.21

1.57

0.77

3.19

Monosomy 5q

0.02

1.83

1.09

3.07

OS

Age ≥50 years old

0.35

1.37

0.71

2.64

RIC vs MAC

0.07

1.75

0.95

3.24

MK

0.14

1.79

0.82

3.91

Monosomy 5q

0.01

2.02

1.18

3.47

RI

Age ≥50 years old

0.54

1.21

0.65

2.25

RIC vs MAC

0.13

1.58

0.87

2.88

Monosomy 5q

0.03

1.84

1.06

3.19

  1. Abbreviations: N number, LFS leukaemia-free survival, OS overall survival, RI relapse incidence, HR hazard ratio, CI confidence interval, MAC myeloablative conditioning, RIC reduced-intensity conditioning, MK monosomal karyotype