Fig. 1

Expression of MAGL is upregulated in HCC patients and its prognostic significance. a Representative immunostaining images of MAGL levels in HCC tissues and corresponding peritumor tissues. Scale bar, 50 μm. MAGL levels were markedly higher in tumor tissues than in peritumor tissues. b Western blot analysis of MAGL levels in HCC tissues and corresponding peritumor tissues. c The expression of MAGL in 27 tumor samples were analyzed by qRT-PCR analysis. The average mRNA level of MAGL was significantly higher in tumor tissues than in peritumor tissues. d Immunohistochemical staining analyses of MAGL expression in 170 HCC patients and representative images are shown. Scale bar, 50 μm. e, f Kaplan–Meier analysis for overall survival and time to recurrence of HCC patients according to MAGL expression. MAGL overexpression in HCC predicts poorer overall survival times and recurrence rates. Data, mean + SD. ***P < 0.001