Fig. 2From: TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemiaTIGAR showed a high expression in human leukemia cell lines, and glycolysis induced the expression of TIGAR. a, b TIGAR mRNA and protein was compared among multiple leukemia cell lines and normal cells. c TIGAR mRNA level was compared by real time PCR in both HL-60 and NB-4 cells treated with or without CoCl2 and 2-DG. d Western blotting showed the expression of TIGAR in HL-60 cells with or without TIGAR knockdown. e Western blotting showed the expression of TIGAR in K562 cells with or without TIGAR overexpressionBack to article page