Table 4 Multivariate analysis of factors predicting for transplantation outcomes in patients surviving leukemia-free 2 years after transplantation

Factor

HR

(95 % CI)

P value

HR

(95 % CI)

P value

HR

(95 % CI)

P value

RIC vs. MAC

0.36

(0.18–0.75)

0.006

1.14

(0.64–2.03)

0.65

0.77

(0.49–1.19)

0.24

CR2 vs. CR1

0.55

(0.18–1.65)

0.29

2.44

(1.28–4.68)

0.007

1.55

(0.89–2.70)

0.12

Advanced vs. CR1

2.28

(1.07–4.85)

0.03

1.68

(0.82–3.44)

0.16

1.91

(1.14–3.21)

0.01

In vivo T cell depletion

1.34

(0.60–2.99)

0.47

1.06

(0.60–1.88)

0.83

1.17

(0.74–1.86)

0.49

Age >55 years

1.82

(0.96–3.48)

0.07

1.21

(0.73–2.02)

0.46

1.37

(0.92–2.04)

0.12

F → M

1.72

(0.92–3.22)

0.09

1.46

(0.85–2.51)

0.17

1.53

(1.02–2.29)

0.04

 Intermediate vs. good

0.35

(0.12–0.97)

0.04

8.09

(1.08–60.79)

0.04

1.43

(0.62–3.30)

0.40

 Poor vs. good

0.18

(0.04–0.82)

0.03

9.82

(1.16–82.79)

0.04

1.29

(0.47–3.56)

0.63

 Missing

0.34

(0.10–1.13)

0.08

5.54

(0.69–44.58)

0.11

1.14

(0.45–2.87)

0.79

Year of SCT

1.01

(0.87–1.17)

0.90

1.03

(0.91–1.16)

0.62

1.02

(0.93–1.12)

0.67

Patient CMV +

1.19

(0.61–2.35)

0.61

0.86

(0.51–1.47)

0.59

0.98

(0.65–1.47)

0.90

Donor CMV +

1.27

(0.65–2.47)

0.49

0.74

(0.45–1.23)

0.25

0.89

(0.60–1.32)

0.56

PBSC vs. BM

0.80

(0.37–1.76)

0.59

1.11

(0.54–2.32)

0.77

0.94

(0.55–1.59)

0.81

Chronic GVHD before 2 years

2.04

(1.06–3.92)

0.03

0.84

(0.52–1.38)

0.50

1.15

(0.78–1.70)

0.47