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Table 1 Patient characteristics

From: Long-term survival and late events after allogeneic stem cell transplantation from HLA-matched siblings for acute myeloid leukemia with myeloablative compared to reduced-intensity conditioning: a report on behalf of the acute leukemia working party of European group for blood and marrow transplantation

 

MAC

(n = 701)

RIC

(n = 722)

P value

Age (median, years)

54 (50–72)

57 (50–75)

<0.0001

Gender (male)

381 (54 %)

395 (55 %)

0.89

F → M

157 (23 %)

193 (27 %)

0.05

Cytogenetics

 Good

31 (8 %)

43 (8 %)

0.19

 Intermediate

316 (77 %)

393 (72 %)

 Poor

66 (16 %)

112 (20 %)

 Missing

288

174

Status at SCT

 CR1

443 (63 %)

450 (62 %)

0.01

 CR2

84 (12 %)

122 (17 %)

 Advanced

174 (25 %)

150 (21 %)

Stem cell source

(PBSC)

515 (73 %)

665 (92 %)

<0.0001

In vivo T cell depletion

81 (12 %)

239 (33 %)

<0.0001

 ATG

55 (8 %)

172 (24 %)

 Alemtuzumab

26 (4 %)

67 (9 %)

Patient CMV +

336 (66 %)

452 (73 %)

0.02

Donor CMV +

284 (58 %)

398 (65 %)

0.009

Year of SCT (median, range)

2002 (1997–2005)

2003 (1997–2005)

<0.0001

  1. Abbreviations: MAC myeloablative conditioning, RIC reduced-intensity conditioning, F → M female donor to male recipient, SCT stem cell transplantation, PBSC peripheral blood stem cell, ATG anti-thymocyte globulin
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Journal of Hematology & Oncology

ISSN: 1756-8722

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