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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Targeting of PI3K/AKT/mTOR pathway to inhibit T cell activation and prevent graft-versus-host disease development

Fig. 4

Effect of BKM120 and BEZ235 on expression of T cell activation markers. Percentage of IFN-γ+ (a), granzyme B+ (b), and CD25+ (c) cells among CD4+ and CD8+ T cells, unstimulated or stimulated in the presence of different concentrations of BKM120 and BEZ235. Data represent the mean + SD from five independent experiments. d MFI of CD25 expression was calculated from four independent experiments. #p < 0.05 with respect to stimulated untreated samples (0 μM)

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Journal of Hematology & Oncology

ISSN: 1756-8722

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