Table 1 Clinical and biological characteristics of the 200 CLL patients

Age, median yrs (range)

67.6 (38.3–89.9)

Sex m/f

121/79

Binet stage a/b/c

161/25/14

CD38 neg/pos

121/79

ZAP-70 neg/pos

143/37

IGVH mut/unmut

105/91

13q14 deletion yes/no

104/96

Trisomy 12 yes/no

32/168

11q22 deletion yes/no

20/180

17p13 deletion yes/no

9/191

FISH fav/int/unfav

142/30/28

Complex karyotype no/yes

167/28

Mutated patients by NGS no/yes

116/84

No. of mutations by NGS 0/1/2/3/4

116/48/24/8/4

TP53 mut/WT

16/184

TP53 disruption yes/no

19/181