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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: Histologic and molecular analysis of patient derived xenografts of high-grade serous ovarian carcinoma

Fig. 1

A Sketch diagram illustrating the work flow for PDX for human HGSC. HGSC tissue were collected from patients (defined as P0) and divided into three aliquots for PDX (small (~3 × 3 × 2 mm) fragments of tissues for subcutaneous (SQ) xenograft as P1), for snap frozen (for later DNA and RNA extraction) and for formalin-fixed and paraffin-embedded (FFPE) preparation (for TMA and immunohistochemistry (IHC) analysis). The extended passages (P2-P4) of tumor xenografts were established for gene profiling analysis and further histological and molecular analysis

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Journal of Hematology & Oncology

ISSN: 1756-8722

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