Fig. 4

Baseline NF-kB activity between ALL and AML patients and impact of bortezomib treatment. Pre-treatment NF-kB activity measurements determined by p65-ELISA in PBMC of acute leukaemia patients comparing a NF-kB activity of pre-B ALL (n = 26), T-ALL (n = 10) and AML (n = 12) patients, and b NF-kB activity prior to treatment compared to 6 and 24 h after bortezomib-containing chemotherapy in pre-B ALL patients that reached CR (n = 16), and c pre-B ALL patients that did not reach CR (n = 10). The line denotes the mean