All patients | PV | ET | PMF | Post-PV-MF | Post-ET-MF | MPN-U | p value# | |
---|---|---|---|---|---|---|---|---|
Antiplatelet drugs | ||||||||
ASSa; n (%) | 248 (57.4) n = 432 | 92 (67.2) n = 137 | 83 (61.5) n = 135 | 45 (42.9) n = 105 | 11 (61.1) n = 18 | 10 (52.6) n = 19 | 7 (38.9) n = 18 | 0.0026 |
P2Y12 antagonista; n (%) | 27 (6.4) n = 425 | 9 (6.7) n = 134 | 13 (9.7) n = 134 | 4 (3.9) n = 104 | 0 (0) n = 17 | 0 (0) n = 18 | 1 (5.6) n = 18 | 0.4064 |
Anticoagulants | ||||||||
VKA; n (%) | 43 (9.8) n = 437 | 14 (10.1) n = 138 | 13 (9.5) n = 137 | 6 (5.6) n = 107 | 4 (21.1) n = 19 | 3 (16.7) n = 18 | 3 (16.7) n = 18 | 0.1511 |
Rivaroxaban; n (%) | 8 (1.8) n = 437 | 3 (2.2) n = 138 | 1 (0.7) n = 137 | 4 (3.7) n = 107 | 0 (0) n = 19 | 0 (0) n = 18 | 0 (0) n = 18 | 0.6151 |
Heparin; n (%) | 16 (3.8) n = 417 | 4 (3.1) n = 131 | 4 (3.1) n = 131 | 5 (4.9) n = 103 | 2 (11.1) n = 18 | 1 (5.9) n = 17 | 0 (0) n = 17 | 0.4345 |
Anti-MPN therapyb | ||||||||
Watch wait; n (%) | 226c (51.7) n = 437 | 79 (57.7) n = 137 | 72 (52.9) n = 136 | 49 (46.2) n = 106 | 7 (33.3) n = 21 | 6 (31.6) n = 19 | 13 (72.2) n = 18 | 0.0321 |
Hydroxyurea; n (%) | 215 (49.2) n = 437 | 82 (59.9) n = 137 | 67 (49.3) n = 136 | 38 (35.9) n = 106 | 10 (47.6) n = 21 | 9 (47.4) n = 19 | 9 (50) n = 18 | 0.0151 |
Anagrelide; n (%) | 66 (15.1) n = 437 | 15 (11.0) n = 137 | 32 (23.5) n = 136 | 11 (10.4) n = 106 | 3 (14.3) n = 21 | 4 (21.1) n = 19 | 1 (5.6) n = 18 | 0.0255 |
Ruxolitinib; n (%) | 87 (19.9) n = 437 | 15 (11.0) n = 137 | 5 (3.7) n = 136 | 43 (40.6) n = 106 | 11 (52.4) n = 21 | 12 (63.2) n = 19 | 1 (5.6) n = 18 | <0.0001 |
IMIDe; n (%) | 21 (4.8) n = 437 | 2 (1.5) n = 137 | 0 (0) n = 136 | 15 (14.2) n = 106 | 2 (9.5) n = 21 | 1 (5.3) n = 19 | 1 (5.6) n = 18 | <0.0001 |
IFNα; n (%) | 40 (9.2) n = 437 | 12 (8.8) n = 137 | 15 (11.0) n = 136 | 9 (8.5) n = 106 | 2 (9.5) n = 21 | 1 (5.3) n = 19 | 1 (5.6) n = 18 | 0.9681 |
SCT; n (%) | 20 (4.6) n = 439 | 3 (2.2) n = 139 | 0 (0) n = 134 | 12 (11.1) n = 108 | 2 (9.5) n = 21 | 2 (10.5) n = 19 | 1 (5.6) n = 18 | <0.0001 |