Fig. 2From: Synergism between the mTOR inhibitor rapamycin and FAK down-regulation in the treatment of acute lymphoblastic leukemiaTargeting FAK via RNAi enhanced the growth-inhibitory effects of rapamycin. a FAK protein (i) and mRNA expression (ii) in REH-empty vector and REH-FAK shRNA cells. b The mTOR inhibitor rapamycin and FAK down-regulation inhibited the proliferation of REH cells. REH-empty vector or REH-FAK shRNA cells were plated in 96-well plates and cultured with rapamycin (0–1000 nM). After 2 days (i) or 3 days (ii), the cells were treated with CCK-8 (10 μl/well) for 2 h and the absorbance was measured. The results represent the mean ± S.D. of three experiments performed in triplicateBack to article page