Fig. 3
From: Haplo-insufficiency of both BubR1 and SGO1 accelerates cellular senescence
BubR1 +/− SGO1 +/− MEFs express SA-β-Gal much earlier than wild-type BubR1 +/− or SGO1 +/− MEFs. a Primary MEFs of various genetic backgrounds (wild-type and BubR1 +/− SGO1 +/−) at passage 3 were stained for senescence-associated β-Gal activity. b Primary MEFs of various genetic backgrounds (wild-type BubR1 +/−, SGO1 +/−, and BubR1 +/− SGO1 +/−) at passage 3 were stained for senescence-associated β-Gal activity. β-Gal-positive cells were recorded. Summarized data from three independent experiments are shown