Table 1 Summary of the top pathways highlighted by GSEA on the total differentially expressed genes
HR-MDS versus FVB/N | AML post MDS versus FVB/N |
|---|---|
Adipogenesis | Adipogenesis |
Androgen response | Allograft rejection |
Angiogenesis | Androgen response |
Bile acid metabolism | Apical junction |
Coagulation | Bile acid metabolism |
Complement | Cholesterol homeostasis |
E2F targets | Coagulation |
Estrogen response late | Complement |
Fatty acid metabolism | E2F targets |
G2M checkpoint | epitheliall mesenchymal transition |
Glycolysis | G2M checkpoint |
Kras signaling | Glycolysis |
Mitotic spindle | Hedgehog-signaling |
mTORC1 signaling | Mitotic spindle |
Myc targets | Oxidative phosphorylation |
Oxidative phosphorylation | Pancreas beta cells |
UV response-dn | Spermatogenesis |
Xenobiotic metabolism | Xenobiotic metabolism |