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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

Fig. 4

qRT-PCR validation of the GEP microarray data (blue) in Sca1+ cells purified from BM or spleen of another set of HR-MDS mice (two different hues of orange), and CD34+ cells purified from MDS patients (green) compared to FBV/N or CD34 BM cells, respectively. Data expressed as fold change of expression of several genes of three pathways shown (angpt1 (signal transduction); cox4i1 and ndufv2 (oxidative metabolism); sdc1 (DNA processing)). qRT-PCR fold changes shown here are represented as the average of three experiments

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