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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: Establishment and characterization of a novel MYC/BCL2 “double-hit” diffuse large B cell lymphoma cell line, RC

Fig. 3

Conventional cytogenetics and FISH analysis of RC cells. a Representative karyotype of RC cells. Red arrows point to t(2;8)(p12;q24.2) translocation, and blue arrows point to t(14;18)(q32;q21.3) translocation also showing an extra copy of der(18)t(14;18) in the karyotype. b FISH analysis confirmed t(14;18) in RC cells. IGH/BCL2 dual-color, dual-fusion translocation probes were used. Green: probe for the immunoglobulin heavy chain gene; red: probe for the BCL2 gene; yellow: IGH-BCL2 fusion gene signal. c FISH analysis of MYC gene rearrangement, showing one red and one green on the der(8)t(2;8) and der(2)t(2;8), respectively

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Journal of Hematology & Oncology

ISSN: 1756-8722

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