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Table 3 Validated significantly differentially expressed miRNAs in the plasma of responsive and resistance groups in 17 couple of patients with EGFR 19 mutation

From: Identification of plasma microRNA profiles for primary resistance to EGFR-TKIs in advanced non-small cell lung cancer (NSCLC) patients with EGFR activating mutation

miRNA

Responsive group

Resistant group

P-valuea

miR-21

135.98±26.44

182.91±47.63

0.01

miR-27a

22.38±5.66

131.85±53.75

0.01

miR-218

1.59±0.714

5.09±1.65

0.03

  1. aWilcoxon test (P<0.05)