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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model

Fig. 4

Western blot analysis suggests a correlation between p-Akt and PCNA levels and tumor size regardless of genotype in EphA4 +/+ EphA7 −/− Smo, EphA4 +/− EphA7 −/− Smo, and EphA4 −/− EphA7 −/− Smo mice. a Western blot analysis in tumor tissues indicated expression of p-Akt and PCNA correlative of tumor size. Lysates were collected from mice and Western blot analysis was done to determine the expression of p-Akt, total Akt, and PCNA. b Densitometric analysis of p-Akt expression (*p ≤ 0.05) and c PCNA levels (p = not significant) in EphA4 +/+ EphA7 −/− Smo, EphA4 +/− EphA7 −/− Smo, and EphA4 −/− EphA7 −/− Smo tumors. Data represent mean ± standard deviation from different tumor tissues

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