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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model

Fig. 2

Western blot analysis shows altered expression of p-Akt and PCNA that related to tumor size and genotype in ephrin-A5 −/− Smo mouse model. a Western blot analysis in representative tumor sections suggests a decrease in p-Akt and PCNA expression in smaller tumors (<10 mm3) with loss of the ephrin-A5 gene. Total Akt levels seem to be unchanged. b Densitometric analysis of p-Akt expression (*p ≤ 0.05) and c PCNA expression (p = not significant) in ephrin-A5 +/+ Smo versus ephrin-A5 −/− Smo tumors. Data represent mean ± standard deviation from different tumor tissues

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