Skip to main content

Table 2 Univariate analysis of prognosis

From: Clinical significance of high-dose cytarabine added to cyclophosphamide/total-body irradiation in bone marrow or peripheral blood stem cell transplantation for myeloid malignancy

Variables

 

Overall mortality

 

HR

(95 % CI)

p

Conditioning

CY/TBI

(Reference)

 

HDCA/CY/TBI

1.50

(1.29–1.74)

<0.01*

Other variables

Sex

Female

(Reference)

 

Male

1.00

(0.88–1.14)

0.96

Age

≤49

(Reference)

 

≥50

1.93

(1.65–2.25)

<0.01*

PS

0–1

(Reference)

 

≥2

2.20

(1.74–2.80)

<0.01*

HCT-CI

≤2

(Reference)

 

≥3

1.90

(1.46–2.47)

<0.01*

CMV sero-status

Negative

(Reference)

 

Positive

1.24

(1.04–1.48)

0.02*

Diagnosis

AML

(Reference)

 

MDS

0.61

(0.49–0.75)

<0.01*

Disease risk

Standard

(Reference)

 

High

2.38

(2.10–2.71)

<0.01*

Days from diagnosis to HCT

≤240

(Reference)

 

≥241

0.89

(0.78–1.01)

0.08

Donor

Rel-BM

(Reference)

 

Rel-PB

1.16

(0.96–1.40)

0.13

UR-BM

1.11

(0.95–1.31)

0.20

HLA mismatch

Matched

(Reference)

 

Mismatched

1.25

(1.01–1.43)

<0.01*

Sex mismatch

Matched

(Reference)

 

M to F

1.04

(0.89–1.22)

0.60

F to M

1.16

(0.99–1.36)

0.07

ABO mismatch

Matched

(Reference)

 

Minor

0.90

(0.75–1.07)

0.23

Major

1.11

(0.93–1.32)

0.23

Both

0.83

(0.64–1.07)

0.15

GVHD prophylaxis

CyA based

(Reference)

 

Tac based

1.01

(0.89–1.15)

0.87

Year of HCT

≤2008

(Reference)

 

≥2009

0.86

(0.75–0.99)

0.04*

  1. Other abbreviations are explained in Table 1
  2. HR hazard ratio, CI confidence interval
  3. *Indicates statistically significant