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Table 2 Morphometric features of PaCSs in granulocytes and platelets of four CML patients and three healthy subjects

From: Particulate cytoplasmic structures with high concentration of ubiquitin-proteasome accumulate in myeloid neoplasms

 

Cells with PaCSs (%)

PaCS area/total cytoplasm area (%)

Number of PaCSs/cytoplasm area unit (n/nm2 × 108)

Number of PaCSs/cell

Granulocytes

CML

67.8 ± 9.1**

7.1 ± 1.9**

53.8 ± 28.4*

8.2 ± 4.5*

Healthy subjects

15.3 ± 12.8

1.1 ± 0.5

5.1 ± 3.9

0.7 ± 0.5

Platelets

CML

56.5 ± 5.0***

7.6 ± 1.2***

47.4 ± 18.7*

0.9 ± 0.3*

Healthy subjects

18.2 ± 4.8

0.9 ± 0.3

11.5 ± 7.6

0.2 ± 0.1

  1. Data are presented as means ± SD
  2. *P < 0.05 vs. healthy subjects
  3. **P < 0.01 vs. healthy subjects
  4. ***P < 0.001 vs. healthy subjects