Skip to main content
Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: Targeting Wnt pathway in mantle cell lymphoma-initiating cells

Fig. 1

Isolation of MCL-ICs. (a) Isolation of MCL-ICs using immunostaining and flow sorting. (b) Immunostaining of isolated MCL-ICs for plasma cell markers CD27/CD38 and natural killer cell markers CD56/CD16 detected by flow cytometry. (c) Detection of gene fusion t (11;14) (q13; q32) in MCL-ICs using fluorescent in situ hybridization, indicated by arrow. (d) qRT-PCR expression of cyclin D1 in MCL-ICs, MCL-non-ICs relative to B-cells. Differences between MCL-ICs and B-cells were significant (P < 0.05) for cyclin D1

Back to article page