From: Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia
 | Precursor B cell ALL | T cell ALL | Total ALL | |||
---|---|---|---|---|---|---|
 | TSIA cont. | TSIA short | TSIA cont. | TSIA short | TSIA cont. | TSIA short |
MTX-Glu1–6 | ||||||
 Correlation coefficient | −0.547* | −0.495* | −0.094 | −0.128 | −0.432* | −0.524* |
  P value | <0.001 | <0.001 | 0.685 | 0.612 | <0.001 | <0.001 |
 Number of patients | 64 | 58 | 21 | 18 | 85 | 76 |
MTX-Glu4–6 | ||||||
 Correlation coefficient | −0.494* | −0.503* | −0.258 | 0.046 | −0.399* | −0.568* |
  P value | <0.001 | <0.001 | 0.336 | 0.875 | 0.001 | <0.001 |
 Number of patients | 54 | 50 | 16 | 14 | 70 | 64 |
TS mRNA | ||||||
 Correlation coefficient | 0.591 | 0.678* | 0.139 | 0.483 | 0.466* | 0.693* |
  P value | 0.056 | 0.045 | 0.701 | 0.187 | 0.033 | 0.001 |
 Number of patients | 11 | 9 | 10 | 9 | 21 | 18 |