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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments

Fig. 2

Assessing the ability to withstand a leukemic allograft in immunodeficient mice. Kaplan-Meyer survival analysis of NSI, IL2Rg−/−, NOD-scid, scid, Rag2−/−, nude, and WT mice injected with a high number (1 × 106, a), medium number (1 × 105, b), and low number (1 × 104, c) of RMA-GFP cells. c Level of RMA-GFP cells in peripheral blood (PB, d), spleen (SP, e), and bone marrow (BM, f) of each mouse with reference to (a). Bars represent the mean percentages of human K562-GFP cells in the PB, SP, and BM of mice from each strain (n = 5)

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