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Table 1 Patient and tumors’ characteristics

From: The impact of taxane-based preoperative chemotherapy in gastroesophageal signet ring cell adenocarcinomas

Patient and tumors’ characteristics before surgery

 

N = 19

Age, years (range)

64

41–81

Gender

No

%

 Male

14

74

 Female

5

26

ECOG-PS

No

%

 0

11

58

 1

5

26

 2

3

16

Location of tumor

No

%

 Distal esophagus or GEJ

8

42

 Stomach

11

58

Clinical TNM stage

No

%

 Stage I

3

16

 Stage II

8

42

 Stage III

8

42

 Stage IV

0

0

Neoadjuvant chemotherapy

No

%

 DCF

7

37

 PET

7

37

 TFOX

3

16

 Docetaxel-Cisplatin

1

5

 Cisplatin-Paclitaxel-Doxorubicin

1

5

Surgery and postoperative variables

 

N = 17

Type of surgery, No (%)

No

%

 Total gastrectomy

8

47

 Subtotal gastrectomy

2

12

 Lewis–Santi esophagectomy*

7

41

Lymphadenectomy extend

No

%

 D1

4

31

 Modified D2

6

46

 D2

3

23

 Missing

4

Resection

No

%

 R0

12

80

 R1

3

20

 R2

0

0

 Missing

2

Pathological tumor classification

No

%

 pT0

1

6

 pT1

2

13

 pT2

3

19

 pT3

5

31

 pT4

5

31

 Missing

1

Pathologic nodal classification

No

%

 pN0

2

13

 pN1

6

38

 pN2

3

19

 pN3

5

31

 Missing

1

Pathologic metastatic stage

No

%

 pM0

15

88

 pM1

2

12

Adjuvant treatment

No

%

 DCF

3

18

 Docetaxel-Cisplatin

1

6

 TFOX

1

6

 mFOLFOX6

6

35

 EOX

2

12

 Chemoradiotherapy

2

12

 No adjuvant treatment

2

12

  1. ECOG-PS Eastern Cooperative Oncology Group—performance status, GEJ gastroesophageal junction, DCF 3 cycles of docetaxel (75 mg/m2 d1), cisplatin (75 mg/m2 d1), and 5-fluorouracil (750 mg/m2/d on continuous perfusion on days 1 to 5), every 3 weeks, PET 8 cycles of cisplatin (30 mg/m2 d1), epirubicin (50 mg/m2 d1), and paclitaxel (80 mg/m2 d1), every week, TFOX docetaxel (50 mg/m2), oxaliplatin (85 mg/m2), leucovorin (400 mg/m2) and 5FU continuous infusion 48 h (2400 mg/m2), S surgery alone, D1 lymphadenectomy limited to regional lymph nodes, modified D2 extended lymph node dissection without pancreatectomy and splenectomy, D2 extended lymph node dissection with pancreatectomy and/or splenectomy, mFOLFOX6 oxaliplatin, leucovorin, 5FU bolus and 5FU continuous infusion 48 h, EOX epirubicin, oxaliplatin and capecitabine
  2. *Oesophagectomy via abdominal and right thoracic approaches