Skip to main content

Table 1 Clinicopathologic associations of GAS5 expression in lung adenocarcinoma

From: The long non-coding RNA, GAS5, enhances gefitinib-induced cell death in innate EGFR tyrosine kinase inhibitor-resistant lung adenocarcinoma cells with wide-type EGFR via downregulation of the IGF-1R expression

Clinical parameters

No. of cases

Relative GAS5 expression

  

Low

High

P valuea

Age

   

0.500

>60 years

39

19

20

 

≤60 years

33

17

16

 

Gender

   

0.479

Male

37

20

17

 

Female

35

16

19

 

Smoking

   

0.151

Non-smoker

42

18

24

 

Smoker

30

18

12

 

Differentiation

   

0.03**

Well

26

14

12

 

Moderate-Poor

46

36

10

 

Maximum diameter

   

0.03**

<3 cm

26

14

12

 

≥3 cm

46

36

10

 

Lymphatic metastasis

   

0.131

Absent

41

27

14

 

Present

31

25

6

 

Distal metastasis

   

1.000

M0

68

34

34

 

M1

4

2

2

 

TNM stage

   

0.047**

I–II

51

32

19

 

III–IV

21

18

3

 

CEA

   

0.583

Positive

34

16

18

 

Negative

38

18

20

 

CA19-9

   

0.500

Positive

39

19

20

 

Negative

33

17

16

 

CA125

   

0.577

Positive

29

16

13

 

Negative

43

29

24

 
  1. aChi-squared test. **P < 0.05.